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Journal of Geriatric Psychiatry and Neurology
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No Long-Term Effect of Behavioral Treatment on Psychotropic Drug Use for Agitation in Alzheimer's Disease Patients

Myron F. Weiner, MD

Rochelle E. Tractenberg, PhD, MPH

Mary Sano, PhD

Rebecca Logsdon, PhD

Linda Teri, PhD

Douglas Galasko, MD

Anthony Gamst, PhD

Ron Thomas, PhD

Leon J. Thal, MD

To determine if teaching caregivers behavior management techniques (BMTs) reduces long-term psychotropic use in Alzheimer's disease (AD) patients, we examined 12-month follow-up data from a 4-month randomized study com paring placebo, BMTs, trazodone, and haloperidol for the treatment of agitated behaviors in persons with AD. After 4 months, treatment was allowed with any agent. Between 42.8% and 51% of AD patients received additional psy chotropics between 4 and 12 months. The relative risk of being prescribed any psychotropic drug after the 4-month trial was at or about 1.0 for subjects in each drug arm or placebo arm versus BMTs. We concluded that teaching caregivers BMTs did not diminish long-term prescription of psychotropic drugs. (J Geriatr Psychiatry Neurol 2002; 15:95-98).

Journal of Geriatric Psychiatry and Neurology, Vol. 15, No. 2, 95-98 (2002)
DOI: 10.1177/089198870201500208
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