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Poststroke Depression in Chinese Patients: Frequency, Psychosocial, Clinical, and Radiological Determinants

Department of Psychiatry, Chinese University of Hong Kong, Hong Kong, SAR, China

Sandra S. M. Chan, MRCPsych

Department of Psychiatry, Chinese University of Hong Kong, Hong Kong, SAR, China

Helen F. K. Chiu, FRCPsych

Department of Psychiatry, Chinese University of Hong Kong, Jockey Club Centre for Positive Ageing, Hong Kong, SAR, China

Gabor S. Ungvari, FRCPsych

Department of Psychiatry, Chinese University of Hong Kong, Hong Kong, SAR, China

Ka Sing Wong, MD

Department of Medicine and Geriatrics, Chinese University of Hong Kong, Hong Kong, SAR, China

Timothy C. Y. Kwok, MRCP

Department of Medicine and Geriatrics, Chinese University of Hong Kong, Hong Kong, SAR, China

Vincent Mok, MRCP

Department of Medicine and Geriatrics, Chinese University of Hong Kong, Hong Kong, SAR, China

K. T. Wong, MD

Department of Diagnostic Radiology and Organ Imaging, Hong Kong, SAR, China

Polly S. Richards, MBBS

Department of Diagnostic Radiology and Organ Imaging, Hong Kong, SAR, China

Anil T. Ahuja, MD

Department of Diagnostic Radiology and Organ Imaging, Hong Kong, SAR, China

This study attempted to evaluate the psychosocial, clinical, and radiological predictors of poststroke depression (PSD) in Chinese patients. One hundred eighty-nine patients participated in the study. Three months after the index stroke, a psychiatrist administered the Structured Clinical Interview for DSM-IV to all of the patients and made a DSM-IV diagnosis of depression. In addition, a host of demographic, clinical, and radiological variables were examined. Thirty-one (16.4%) of the patients had a diagnosis of PSD that included major depression (n = 11, 5.8%,), minor depression (n = 16, 8.5%), or dysthymia (n = 4, 2.1%). Univariate analysis revealed that PSD was associated with female gender, a lower level of education, a lower Lubben Social Network Scale (LSNS) score, subcortical infarcts, and lesions in the anterior cerebral artery (ACA) territory, and the Modified Life Event Scale (MLES) score was borderline for statistical significance. Multivariate logistic regression analysis suggested that female gender, a high MLES score, and subcortical and ACA lesions were independent risk factors for PSD and that a high LSNS score was a protective factor. (J Geriatr Psychiatry Neurol 2005; 18:45-51)

Key Words: stroke • depression • risk factors • Chinese

Journal of Geriatric Psychiatry and Neurology, Vol. 18, No. 1, 45-51 (2005)
DOI: 10.1177/0891988704271764


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