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DOI: 10.1177/089198878900200207 © 1989 SAGE Publications Lifetime Course of Chronic Depression in Older MenDepartments of Psychiatry, Yale University, New Haven
Departments of Psychiatry, Yale University, New Haven
University of Connecticut, Farmington The lifetime course of illness in older outpatient men who remained symptomatic despite adequate pharmacologic treat ment for depression was examined. A bimodal distribution of age of onset of first major depression was found, with 75% having onset before age 35 years and 25% having onset after age 50 years. At all ages, episodes of chronic depression developed after episodes of major depression and appeared to be partially resolved major depression. In 88% of patients, anxiety disorders developed before age 35 years, preceded onset of other disorders, and continued throughout the patient's lifetime. Seventy percent developed alcoholism and 25% had a medical illness that impaired function to a signifi cant degree. The importance of obtaining a lifetime course of illness in older patients is discussed. ( J Geriatr Psychiatry Neurol 1989;2:89-95).
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