This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Falk, W. E. Articles by Nixon, R. A. Search for Related Content PubMed Articles by Falk, W. E. Articles by Nixon, R. A. Social Bookmarking                         What's this?

Fluoxetine Versus Trazodone in Depressed Geriatric Patients

Department of Psychiatry, Harvard Medical School, and the Massachusetts General Hospital, Boston, MA

Jerrold F. Rosenbaum

Department of Psychiatry, Harvard Medical School, and the Massachusetts General Hospital, Boston, MA

Michael W. Otto

Department of Psychiatry, Harvard Medical School, and the Massachusetts General Hospital, Boston, MA

Paul M. Zusky

Department of Psychiatry, Harvard Medical School, and the Massachusetts General Hospital, Boston, MA

Jeffrey B. Weilburg

Department of Psychiatry, Harvard Medical School, and the Massachusetts General Hospital, Boston, MA

Ralph A. Nixon

Department of Psychiatry, Harvard Medical School, and the Massachusetts General Hospital, Boston, MA

A total of 27 subjects began active treatment in this double-blind study comparing the efficacy and safety of trazodone and fluoxetine in geriatric depressed patients, but only 13 completed 6 weeks on study medication. Both agents were effective according to weekly and endpoint analyses, and there was no evidence of significant effects on blood pressure, pulse, or weight. Separate analysis of patients who had received an adequate trial of medication indicated a trend toward relatively more fluoxetine-treated patients meeting clinical criteria for resolved depression. (J Geriatr Psychiatry Neurol 1989;2:208-214.)

Journal of Geriatric Psychiatry and Neurology, Vol. 2, No. 4, 208-214 (1989)
DOI: 10.1177/089198878900200407


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				G. Gartlehner, B. N. Gaynes, R. A. Hansen, P. Thieda, A. DeVeaugh-Geiss, E. E. Krebs, C. G. Moore, L. Morgan, and K. N. Lohr Comparative Benefits and Harms of Second-Generation Antidepressants: Background Paper for the American College of Physicians Ann Intern Med, November 18, 2008; 149(10): 734 - 750. [Abstract] [Full Text] [PDF]