This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (4) Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Lee, E. Articles by Mori, E. Search for Related Content PubMed PubMed Citation Articles by Lee, E. Articles by Mori, E. Pubmed/NCBI databases Medline Plus Health Information Alzheimer's Disease Social Bookmarking                         What's this?

Confabulations in Episodic Memory Are Associated With Delusions in Alzheimer’s Disease

Department of Behavioral Neurology and Cognitive Neuro-science, Tohoku University Graduate School of Medicine, Sendai, School of Health and Welfare, Woosong University, Daejeon, Korea, The Tajiri SKIP Center, Tajiri, Japan

Kenichi Meguro, MD, PhD

The Tajiri SKIP Center, Tajiri, Department of Geriatric Behavioral Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan, k-meg{at}umin.ac.jp

Ryusaku Hashimoto, PhD

The Tajiri SKIP Center, Tajiri, Japan

Mitsue Meguro, MSc

The Tajiri SKIP Center, Tajiri, Japan

Hiroshi Ishii, MD, PhD

Department of Behavioral Neurology and Cognitive Neuro-science, Tohoku University Graduate School of Medicine, Sendai, Japan

Satoshi Yamaguchi, MD, PhD

The Tajiri SKIP Center, Tajiri, Japan

Etsuro Mori, MD, PhD

Department of Behavioral Neurology and Cognitive Neuro-science, Tohoku University Graduate School of Medicine, Sendai, Japan

Although confabulations and delusions are observed in Alzheimer’s disease, the relationship between the 2 has not been fully investigated. This study involved 50 patients with Alzheimer’s disease and 10 healthy participants. After the patients were divided into delusional and nondelusional groups, confabulations and cognitive function were assessed. No confabulations appeared in the healthy participants, and only patients with Alzheimer’s disease showed confabulations. The delusional group produced more confabulations on episodic subjects than on semantic subjects. There was a correlation between cognitive impairment and confabulations in semantic memory. These findings suggest that different mechanisms are involved in confabulations between semantic and episodic memories.

Key Words: Alzheimer’s disease • confabulation • delusion

Journal of Geriatric Psychiatry and Neurology, Vol. 20, No. 1, 34-40 (2007)
DOI: 10.1177/0891988706292760


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				P. D. Bruen, W. J. McGeown, M. F. Shanks, and A. Venneri Neuroanatomical correlates of neuropsychiatric symptoms in Alzheimer's disease Brain, September 1, 2008; 131(9): 2455 - 2463. [Abstract] [Full Text] [PDF]