Journal of Geriatric Psychiatry and Neurology

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Free Access - Register Here

Click here to sign up for SAGE Journal Email Alerts today!

Sign In to gain access to subscriptions and/or personal tools.
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Perryman, K. M.
Right arrow Articles by Fitten, L. J.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Perryman, K. M.
Right arrow Articles by Fitten, L. J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Journal of Geriatric Psychiatry and Neurology, Vol. 4, No. 3, 127-133 (1991)
DOI: 10.1177/089198879100400302

Quantitative EEG During a Double-Blind Trial of THA and Lecithin in Patients with Alzheimer's Disease

Kent M. Perryman, PhD

L. Jaime Fitten, MD

Quantitative electroencephalography (EEG) was performed on eight of ten Alzheimer patients in a double-blind, inpatient-outpatient tetrahydroaminoacridine (THA) and lecithin trial. Neuropsychological measures were related to EEG activity. Patient baseline dominant parietal rhythms (DPRs) and power spectral distributions differed significantly from controls. Severity of cognitive impairment was related to the degree of parietal slowing. Inpatient THA treatment resulted in increased DPR frequency in six of eight patients. Four of eight inpatients demonstrated reduced power in the delta and theta bands. During the outpatient long-term treatment phase, six of the patients were able to continue. Three of these improved significantly on tests of cognition. Two of these improved patients demonstrated DPRs with increased fre quency. One of these patients also showed a decrease in slow-wave activity. Thus, THA may accelerate DPRs while re ducing power in the slower EEG bands. However, there appears to be only a tentative coupling between individual quantitative EEG measures and cognitive performance associated with THA administration (J Geriatr Psychiatry Neurol 1991;4:127-133).


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 J Geriatr Psychiatry NeurolHome page
D. P. Holschneider and A. F. Leuchter
Clinical Neurophysiology Using Electroencephalography in Geriatric Psychiatry: Neurobiologic Implications and Clinical Utility
J Geriatr Psychiatry Neurol, October 1, 1999; 12(3): 150 - 164.
[Abstract] [PDF]