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Journal of Geriatric Psychiatry and Neurology
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ECT-Induced Interictal Delirium in Patients With a History of a CVA

Michelle Martin, MD

Department of Psychiatry, Washington University School of Medicine, St Louis, MO.

Gary Figiel, MD

Department of Psychiatry, Washington University School of Medicine, St Louis, MO.

Gregory Mattingly, MD

Department of Psychiatry, Washington University School of Medicine, St Louis, MO.

Charles F. Zorumski, MD

Department of Psychiatry, Washington University School of Medicine, St Louis, MO.

Michael R. Jarvis, MD

Department of Psychiatry, Washington University School of Medicine, St Louis, MO.

Earlier works have documented a high incidence of affective disorders in patients with a history of a cerebrovascular accident (CVA). In general, electroconvulsive therapy (ECT) has been reported to be effective in treating depressed patients with a history of CVA. Recent works have shown that preexisting structural brain changes may predispose patients to develop interictal ECT-induced delirium. However, the incidence of ECT-induced interictal delirium in patients with a history of CVA has not been directly studied. In this pilot study, the authors examined the incidence of ECT-induced interictal delirium in 14 depressed CVA patients compared with 14 elderly depressed controls (without a history of CVA). Interestingly, the overall incidence of delirium was identical in both groups (28.5%). However, consistent with previous works, some patients who had had a recent CVA involving the caudate nucleus appeared more likely to develop delirium. Thirteen of the 14 depressed CVA patients (92%) showed a moderate to significant improvement in their depressive symptoms from ECT. None of the patients developed significant cardiac complications during ECT. (J Geriatr Psychiatry Neurol 1992;5:149–155).

Journal of Geriatric Psychiatry and Neurology, Vol. 5, No. 3, 149-155 (1992)
DOI: 10.1177/002383099200500304


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