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Journal of Geriatric Psychiatry and Neurology
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Antidepressant Treatment of Pathologic Laughing or Crying in Elderly Stroke Patients

Michael J. Panzer, MD

Department of Psychiatry, University of Michigan, Ann Arbor, MI.

Alan M. Mellow, MD, PhD

Department of Psychiatry, University of Michigan, Ann Arbor, MI.

Pathologic laughing or crying (PLC), a complication of many neurologic disorders, involves behavior that is either inappropriate to the context or to the patient's subjective feeling state. It is due to a dysregulation of the motoric components of emotional experience. PLC is distinct from, but often associated with, major depression. The relatively few reports on treatment of PLC are primarily with tricyclic antidepressants. We report the effective treatment of PLC due to stroke in three patients with nortriptyline or fluoxetine. The cases also illustrate the broad spectrum of depressive symptoms (from none to a major depression) seen in patients with PLC. We discuss treatment implications and directions for future research. (J Geriatr Psychiatry Neurol 1992;4:195–199).

Journal of Geriatric Psychiatry and Neurology, Vol. 5, No. 4, 195-199 (1992)
DOI: 10.1177/002383099200500403
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This article has been cited by other articles:


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[Abstract] [PDF]


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