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Journal of Geriatric Psychiatry and Neurology
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Treatment of Depression

Th. R. Payk

Depressions are the most common psychiatric diseases. For treatment, plant extracts have been used for thousands of years: examples are extracts from the (sleeping) poppy (opium), deadly nightshade (Atropa belladonna), Indian hemp (hashish), henbane (hyoscyamine), thorn apple (scopolamine), and St. John's wort (hypericum oil). In addition, psychotherapeutic measures, like playing music, dancing, playing theatre, and also the temple sleep, were used. In the 19th century, the introduction of brome (1826), codeine (1832), chloral hydrate (1869), and paraldehyde (1882), as well as the barbiturates (at the turn of the century) introduced significant improvements in pharmacotherapy. The modern thymoleptica therapy started in 1957 with the introduction of imipramine. Now about 40 active antidepressants are marketed. New drug developments should be characterized mainly by an improvement in tolerance. (J Geriatr Psychiatry Neurol 1994; 7(suppl 1): S3-S5).

Journal of Geriatric Psychiatry and Neurology, Vol. 7, No. 1, S3-S5 (1994)
DOI: 10.1177/089198879400700102
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This article has been cited by other articles:


Home page
 J Geriatr Psychiatry NeurolHome page
G. Harrer and V. Schulz
Clinical Investigation of the Antidepressant Effectiveness of Hypericum
J Geriatr Psychiatry Neurol, October 1, 1994; 7(1): S6 - S8.
[Abstract] [PDF]


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