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Journal of Geriatric Psychiatry and Neurology
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Herbal Products and Other Supplements: Use by Elderly Veterans with Depression and Dementia and Their Caregivers

Helen C. Kales, MD

Psychiatry Service (116A), VA Ann Arbor Healthcare System, 2215 Fuller Road, Ann Arbor, MI, 48105;; Serious Mental Illness Research and Evaluation Center, Health Services Research and Development, VA Ann Arbor Healthcare System, Ann Arbor Michigan; Division of Geriatric Psychiatry, University of Michigan, Ann Arbor kales{at}umich.edu

Frederic C. Blow, PhD

Serious Mental Illness Research and Evaluation Center, Health Services Research and Development, VA Ann Arbor Healthcare System, Ann Arbor, Michigan; Division of Geriatric Psychiatry, University of Michigan, Ann Arbor

Deborah E. Welsh, MS

Serious Mental Illness Research and Evaluation Center, Health Services Research and Development, VA Ann Arbor Healthcare System, Ann Arbor, Michigan

Alan M. Mellow, MD, PhD

Division of Geriatric Psychiatry, University of Michigan, Ann Arbor

The use of herbal products and other "natural" supplements among the US population is on the rise. Limited data suggest that such use among the elderly may correlate with higher education levels as well as psychiatric symptoms. The authors examined herbal/supplement use among elderly veterans with depression and/or dementia (n = 82) and their primarily elderly caregivers (n = 56). Eighteen percent of subjects and 16% of caregivers used herbals/supplements. Seventy-five percent of subjects who used these products during the study period were also taking potentially interacting medications. Given the prior association of herbal/supplement use with higher education levels, a surprising number of elderly veterans with depression and/or dementia (the majority of whom had high school or less education) used these products. As evidenced by missing documentation in many physician notes, subjects may not have discussed their usage of herbals/supplements with their physicians. In light of the possibility of potentially harmful drug interactions, physicians who treat elderly patients should regularly inquire about the use of these products.

Key Words: elderly • alternative medicine • dementia • depression

References

  • 1. Eisenberg DM, Davis RB, Ettner SL, et al. Trends in alternative medicine use in the United States, 1990-1997: results of a followup national survey. JAMA1998; 280:1569-1575.[Abstract/Free Full Text]
  • 2. Kaufman DW, Kelly JP, Rosenberg L, et al. Recent patterns of medication use in the ambulatory adult population of the United States: the Sloane survey. JAMA2002; 287:337-344.[Abstract/Free Full Text]
  • 3. Astin JA. Why patient use alternative medicine: results of a national study. JAMA1998; 279:1548-1553.[Abstract/Free Full Text]
  • 4. Busto UE, Sproule BA, Knight K, et al. Use of prescription and nonprescription hypnotics in a Canadian elderly population. Can J Clin Pharmacol2001; 8:213-221.[Medline] [Order article via Infotrieve]
  • 5. Foster DF, Phillips RS, Hamel MB, et al. Alternative medicine use in older Americans. J Am Geriatr Soc2000; 48:1560-1565.[Medline] [Order article via Infotrieve]
  • 6. Astin JA, Pelletier KR, Marie A, et al. Complementary and alternative medicine use among elderly persons: one-year analysis of a Blue-Shield Medicare supplement. J Gerontol A Biol Sci Med Sci2000; 55:M4-M9.[Abstract]
  • 7. Coleman LM, Fowler LL, Williams ME. Use of unproven therapies by people with Alzheimer’s disease. J Am Geriatr Soc1995; 43:747-750.[Medline] [Order article via Infotrieve]
  • 8. Hogan DB, Elby EM. Complementary medicine use in a dementia clinic population. Alzheimer Dis Assoc Disord1996; 10:63-67.[CrossRef][Medline] [Order article via Infotrieve]
  • 9. Rosenblatt M, Mindel J. Spontaneous hyphema associated with ingestion of ginkgo biloba extract. N Engl J Med1997; 336:1108-1108.[Free Full Text]
  • 10. Matthews MK. Association of ginkgo biloba with intracerebral haemorrhage. Neurology1998; 5:19-33.
  • 11. Galluzi S, Zanetti O, Binetti G, et al. Coma in a patient with Alzheimer’s disease taking low dose trazodone and ginkgo biloba. J Neurol Neurosurg Psychiatry2000; 68:679-683.[Free Full Text]
  • 12. Gordon JB. SSRIs and St. John’s wort: possible toxicity? Am Fam Phys1998; 57950-950.[Medline] [Order article via Infotrieve]
  • 13. Yue Q-Y, Bergquist C, Gerden B. Safety of St. John’s wort (Hypericum perforatum). Lancet2000; 355:576-577.[Medline] [Order article via Infotrieve]
  • 14. Ruschitzka F, Meier PJ, Turina M, et al. Acute heart transplant rejection due to St. John’s wort. Lancet2000; 355:548-549.[CrossRef][Medline] [Order article via Infotrieve]
  • 15. Johne A, Brockmoller J, Bauer S, et al. Pharmacokinetic interaction of digoxin with an herbal extract from St. John’s wort (Hypericum perforatum). Clin Pharmacol Ther1999; 66:338-345.[CrossRef][Medline] [Order article via Infotrieve]
  • 16. Jones BD, Runikis AM. Interaction of ginseng with phenylzine. J Clin Psychopharmacol1987; 7:201-202.[CrossRef][Medline] [Order article via Infotrieve]
  • 17. Janetzky K, Morreale AP. Probable interactions between warfarin and ginseng. Am J Health Syst Pharm1997; 54:692-693.[Free Full Text]
  • 18. Kales HC, Valenstein M. Complexity in late-life depression: impact of confounding factors on diagnosis, treatment and outcomes. J Geriatr Psychiatry Neurol2002; 15:147-155.
  • 19. Agha Z, Lofgren RP, VanRuiswyk JV, et al. Are patients at veterans affairs medical centers sicker? A comparative analysis of health status and medical resource use. Arch Intern Med2000; 160:3252-3257.[Abstract/Free Full Text]
  • 20. Sheikh JI, Yesavage JA. Geriatric depression scale (GDS): recent evidence and development of a shorter version. Clin Gerontol1986; 6:165-173.[CrossRef]
  • 21. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state." A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res1975; 12:189-198.[CrossRef][Medline] [Order article via Infotrieve]
  • 22. McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer’s disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s Disease. Neurology1984; 34:939-944.[Abstract/Free Full Text]
  • 23. Roman GC, Tatemichi TK, Erkinjuntti T, et al. Vascular dementia: diagnostic criteria for research studies. Report of the NINDSAIREN International Workshop. Neurology1993; 43:250-260.[Abstract/Free Full Text]
  • 24. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Washington, DC: American Psychiatric Association, 1994.
  • 25. Linn BS, Linn MW, Gurel L. Cumulative illness rating scale. J Am Geriatr Soc1968; 16:622-626.[Medline] [Order article via Infotrieve]
  • 26. Izzo AA, Ernst E. Interactions between herbal medicines and prescribed drugs. Drugs2001; 61:2163-2175.[CrossRef][Medline] [Order article via Infotrieve]

Journal of Geriatric Psychiatry and Neurology, Vol. 17, No. 1, 25-31 (2004)
DOI: 10.1177/0891988703261998
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