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Journal of Geriatric Psychiatry and Neurology
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*Parkinson's Disease
*Patient Rights
*Pesticides
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Spatial Test for Agricultural Pesticide "Blow-In" Effect on Prevalence of Parkinson’s Disease

J. A. Yesavage, MD

Palo Alto Veterans Affairs Health Care System, Palo Alto, CA, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, yesavage{at}stanford.edu

J. Sheikh, MD

Palo Alto Veterans Affairs Health Care System, Palo Alto, CA, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA

A. Noda, MS

Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA

G. Murphy, MD, PhD

Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA

R. O’Hara, PhD

Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA

R. Hierholzer, MD

Central California Veterans Affairs Health Care System, Fresno, CA, and University of California at San Francisco

M. Battista, PhD

Central California Veterans Affairs Health Care System, Fresno, CA, and University of California at San Francisco

J. W. Ashford, MD, PhD

Palo Alto Veterans Affairs Health Care System, Palo Alto, CA

B. Schneider, MD

Palo Alto Veterans Affairs Health Care System, Palo Alto, CA, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA

J. Hoblyn, MD

Palo Alto Veterans Affairs Health Care System, Palo Alto, CA, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA

H. C. Kraemer, PhD

Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA

J. Tinklenberg, MD

Palo Alto Veterans Affairs Health Care System, Palo Alto, CA, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA

The current study used Department of Veteran’s Affairs (VA) clinical records, State of California pesticide application records, spatial maps of distribution of Parkinson’s disease patients, and pesticide applications to determine if there was evidence for "blow-in" of pesticides as a factor in explaining the prevalence of Central Valley Parkinson’s disease. The results did not support the hypothesis of increasing prevalence of Parkinsonism attributable to wind drift.

Key Words: Parkinson’s disease (Parkinsonism) • pesticides • amphibians • database

References

  • Betarbet R, Sherer TB, MacKenzie G, et al. Chronic systemic pesticide exposure reproduces features of Parkinson’s disease. Nat Neurosci 2000;3:1301-1306.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Gorell JM, Johnson CC, Rybicki BA, et al. The risk of Parkinson’s disease with exposure to pesticides, farming, well water, and rural living. Neurology 1998;50:1346-1350.[Abstract/Free Full Text]
  • Petrovitch H, Ross GW, Abbott RD, et al. Plantation work and risk of Parkinson disease in a population-based longitudinal study. Arch Neurol 2002;59:1787-1792.[Abstract/Free Full Text]
  • Priyadarshi A, Khuder SA, Schaub EA, Priyadarshi SS. Environmental risk factors and Parkinson’s disease: a metaanalysis. Environ Res 2001;86:122-127.[Medline] [Order article via Infotrieve]
  • Semchuk KM, Love EJ, Lee RG. Parkinson’s disease and exposure to agricultural work and pesticide chemicals. Neurology 1992;42:1328-1335.[Abstract/Free Full Text]
  • Ritz B, Yu F. Parkinson’s disease mortality and pesticide exposure in California 1984-1994. Int J Epidemiol 2000;29:323-329.[Abstract/Free Full Text]
  • Priyadarshi A, Khuder SA, Schaub EA, Shrivastava S. A meta-analysis of Parkinson’s disease and exposure to pesticides. Neurotoxicology 2000;21:435-440.[Web of Science][Medline] [Order article via Infotrieve]
  • Yesavage JA, Sheikh J, Noda A, et al. Use of a VA pharmacy database to screen for areas at high risk for disease: Parkinson’s disease and exposure to pesticides. J Geriatr Psychiatry Neurol 2004;17:36-38.[Abstract]
  • Davidson C, Shaffer HB, Jennings MR. Spatial tests of the pesticide drift, habitat destruction, UV-B, and climate-change hypotheses for California amphibian declines. Conservation Biology 2002;16:1588-1601.[CrossRef]
  • Tufte ER. The visual display of quantitative information. Cheshire, Conn: Graphics Press; 1983.

Journal of Geriatric Psychiatry and Neurology, Vol. 19, No. 1, 32-35 (2006)
DOI: 10.1177/0891988705284707


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This Article
Right arrow Abstract Freely available
Right arrow Free Full Text (Free PDF) Free
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Yesavage, J. A.
Right arrow Articles by Tinklenberg, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yesavage, J. A.
Right arrow Articles by Tinklenberg, J.
Right arrowPubmed/NCBI databases
Medline Plus Health Information
*Parkinson's Disease
*Patient Rights
*Pesticides
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

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